Health and Lifestyle Check

£64.99

This is the perfect package for you if you are after a comprehensive analysis of key markers associated with your general health.

Health and Lifestyle Check

Tests Included

Kidney Function

Creatinine is a breakdown product of creatine phosphate that is found in muscle. Serum creatinine is an important indicator of renal health because it is an easily measured by-product of muscle metabolism that is excreted unchanged by the kidneys. Causes of elevated serum creatinine can be attributed to by a variety of lifestyle factors including, consuming creatine supplements, high amounts of animal protein, or performing high intensity exercise. Whilst other causes include impaired kidney function. On the other hand, low serum creatinine can be an indication of the kidneys functioning efficiently. In addition, a low protein diet or reduced muscle mass may also result in a low reading.
The estimated glomerular filtration rate is one of the best tests used to assess how well your kidneys are functioning. The kidneys are composed of thousands of glomeruli which act as tiny filters that are capable of filtering waste from the blood. The eGFR is an estimation of how much blood passes through these glomeruli with each passing minute and can be calculated based on blood creatinine levels, gender, age and weight. A high eGFR indicates optimal functioning of the kidneys. In contrast, a low value for eGFR means your kidneys may not be working to their full potential and can be a sign of kidney disease. eGFR can also be a useful tool in determining the stage of kidney disease which is important in identifying the best treatment for you. Early detection of kidney disease means there could be a better chance of slowing or stopping the progression of the disease. A low eGFR may also be observed in individuals from certain ethnic backgrounds or those with increased muscle mass, in which case impaired kidney function may not be the case.

Liver Function

ALP

The level of alkaline phosphatase in the blood is checked through the ALP test, which is often part of routine blood tests. Alkaline phosphatase (ALP) is an enzyme found mainly in the liver and bones. The levels of this enzyme in the blood is dependent on several factors such as age, sex and blood type. Elevated levels of ALP in the blood could indicate issues relating to the liver, gall bladder or bones. As ALP is non specific, ALP is normally checked in addition to other liver function tests to determine whether the damage has occurred to the liver or the bones. Blood levels of ALP also increase two to four times during pregnancy and in growing teenagers.

ALT

Alanine transferase (ALT) is an enzyme that is produced by the liver. Elevated ALT can be indicative of inflammation of the liver characteristic of liver damage which may be caused by drugs, alcohol or viruses (hepatitis). High intensity exercise can also result in elevated levels of ALT.

CK

Creatine kinase (CK) is an enzyme that exists in various cell types and tissues but found in especially high amounts in the muscle. High levels of CK in the blood can indicate damage to the muscles as CK leaks out of the tissue. Following damage and trauma to the muscles, CK levels will drastically rise, with levels subsiding to normal once the damage is repaired. Individuals with greater muscle mass typically have higher levels of CK.
Gamma GT is an enzyme found within the liver and is typically raised following diseases affecting this tissue or the bile ducts. Elevated ALP on its own cannot distinguish between liver or bone damage, however, when this value is combined with an elevated levels of gamma GT it is indicative of liver disease. Gamma GT can also be used to diagnose alcohol abuse as it is typically raised in the majority of long term drinkers.
Bilirubin is a yellow compound that is produced during the break down of haemoglobin. This is a necessary process in the body's clearance of waste products that arise from the destruction of aged or abnormal red blood cells. Bilirubin is removed from the body via the liver and excreted in bile and urine. The accumulation of bilirubin can result in jaundice which involves the yellowing discoloration of the whites of the eyes in addition to the skin. Elevated levels may indicate the livers inability to remove it from the blood and therefore can be a sign of liver damage. Certain diseases such as Gilberts syndrome or a blocked bile duct can also result in elevated levels of bilirubin.

Proteins

Total Protein describes the total sum of globulin and albumin combined. Levels outside of the normal range can be indicative of kidney or liver disorders. Other causes of abnormal levels include malnutrition.
Albumin is primarily produced by the liver and is an important protein in preventing blood from leaking out of blood vessels. Other functions of albumin range from transporting substances such as medications through the blood to playing a role in the growth and repair of tissues. Elevated levels of albumin are typically caused by dehydration. In contrast, low levels may be indicative of liver disease, inflammation or malnutrition. Levels may also be raised in conditions such as diabetes.
Globulin may be produced by the immune system or the liver and consist of several different proteins with varying roles. For instance, some globulins are capable of binding to haemoglobin while others may be involved in the transport of substances like iron and in fighting infection.

Iron Status

Ferritin is a protein that stores iron and releases it in a controlled fashion. In humans, it acts as a buffer against iron deficiency and iron overload. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body, hence serum ferritin is used as a diagnostic test for iron-deficiency anaemia. Low levels are indicative of anaemia and may be caused by events such as excessive bleeding or lack of iron within the diet. In contrast, elevated ferritin levels could indicate iron overload syndrome or liver damage.

Cholesterol Status

Triglycerides are a type of fat (lipid) that is found within the blood. After a meal, the body converts any calories it doesn't need to use right away into triglycerides. These are then transported to cells where they are stored as fat. Later, the production of hormones can stimulate the release of triglycerides which can be used for energy between meals. The regular overconsumption of greater than those burned may result in hypertriglyceridemia, a condition in which the level of triglycerides are elevated. This can be a risk factor for microvascular disease which affects the tiny blood vessels around the heart. 
Cholesterol is an essential body fat (lipid) that is predominantly derived from the foods we consume, though, is also produced by the liver. Cholesterol is an important component of cell membranes and is also a precursor molecule to a variety of essential hormones. Individuals with high levels of cholesterol in the body are at a significantly increased risk for developing heart disease. However, total cholesterol is a sum of both good (HDL) and bad (LDL) cholesterol therefore, it is necessary to investigate whether the rise in total cholesterol is caused by a high proportion of HDL or LDL as HDL can in fact exhibit protective effects against heart disease.
HDL (high density lipoprotein) cholesterol is often referred to as the "good" cholesterol due to its ability to pick up other forms of excess cholesterol present in the blood and transport this back to the liver where it is broken down and removed from the body. Individuals with increased levels of HDL cholesterol have been found to be associated with a lower risk of developing heart disease.
LDL cholesterol (low density lipoprotein) also known as the "bad" cholesterol is responsible for transporting triglycerides, other fats and other cholesterol to a variety of tissues located throughout the body. Excessive amounts of LDL in the body as a result of the overconsumption of certain foods, can result in fatty deposits accumulating on the walls of the artery. This can subsequently result in the development of atherosclerosis and is associated with an increased risk of heart disease. 
Measurements of Non-HDL cholesterol are important in establishing the total amount of cholesterol present in the blood that serve a non-protective role for the body and are potentially harmful. The value is calculated by subtracting an individuals HDL cholesterol result from the value of total cholesterol. As the value includes a total of all the forms of potentially damaging cholesterol and not just LDL alone, it is considered to be a greater biomarker for cardiovascular risk.
HDL (high density lipoprotein) cholesterol is often referred to as the "good" cholesterol due to its ability to pick up other forms of excess cholesterol present in the blood and transport this back to the liver where it is broken down and removed from the body. Individuals with increased levels of HDL cholesterol have been found to be associated with a lower risk of developing heart disease.

Inflammation Marker

C-Reactive Protein (CRP) is a protein that increases in response to inflammation detected within the body - though it cannot be used to identify the exact location of where this inflammation is occurring. On the other hand, high Sensitivity CRP (CRP-hs) is used to detect low-level inflammation and can give more of an indication of the location of the inflammation as this type has been found to be associated with damaged blood vessels. Damage to blood vessels can increase an individuals likelihood of suffering a stroke or heart attack. Therefore, an elevated hs-CRP may be considered a risk factor for cardio-vascular disease.

Vitamins

Vitamin B-12 is an important vitamin that is involved in several processes ranging from the production of red blood cells to aiding in the correct functioning of the nervous system. Consequently, prolonged vitamin B12 deficiency can result in anaemia or nerve damage respectively. In contrast, elevated levels of vitamin B12 can be an indication of a liver or blood disorder. The most common cause of raised vitamin B12 is due to over supplementation.
"Interestingly enough, vitamin D is in fact a hormone that is produced by the body and requires exposure to sunlight for activation. In addition. it can be found in certain foods such as egg yolks, fish and fortified dairy and grain products. Vitamin D is an essential component required for maintaining bone strength due to its role in aiding the intestines ability to absorb calcium. Low levels of vitamin D may be associated with secondary low bone mineral density and hyperparathyroidism. Consequently, these patients have a greater risk of suffering fractures and osteoporosis. Other conditions such as rickets and osteocalcin may also develop as a result of continued vitamin D deficiency over a long period of time. "

How it works

Collect Sample

We send you an easy-to-use kit to collect your blood sample.

Post Sample

Post your sample to our lab in the prepaid envelope provided.

View Results

View results securely in your own personal dashboard.

About this test

This is the perfect package for you if you are after a comprehensive analysis of key markers associated with your general health. It can help establish if lifestyle choices such as your diet are having an impact on the levels of key analytes in your blood. It can also help you understand if you are at risk of certain conditions such as cardiovascular disease.

Included in the package are tests assessing kidney and liver function, the health of your heart, iron and nutritional status and the presence of inflammation within the body. Together this can provide you with a thorough overview of the overall health of your body.

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